再生药的发展领域,主要集中在修复和取代受损细胞组织或病源组织。干细胞有自我修复功能。胚胎干细胞可以开发成身体内任何形式的细胞组织,成体干细胞的功能是维护或修复身体内部的细胞。Boiheringer Ingelheim的寻找目标是:调动,刺激,分化新的内源性干细胞分子结构的途径。
投标截止时期2016年6月24日,
投标网址:https://www.innocentive.com/ar/challenge/9933855
原文
Mobilization, Stimulation, and Differentiation of Endogenous Stem Cells
TAGS:
Chemistry, Royal Society of Chemistry, Life Sciences, Ideation
AWARD: $15,000 USD | DEADLINE: 6/24/16 | ACTIVE SOLVERS: 51 | POSTED: 4/25/16
1. The Challenge and qualification for the award
During early development, embryonic stem cells are undifferentiated cells that can be stimulated to proliferate and develop into all different cell types. In adults, these endogenous cells are found in tissues and they can divide either to replenish the stem cell population or differentiate into specialized cells of the tissue in which they reside. These adult stem cells function as an internal maintenance or repair system, so it would be beneficial to be able to direct and enhance this regenerative capacity. Therefore, Boehringer Ingelheim (the Seeker) desires the identification of new molecular mechanisms and pathways involved in mobilization, stimulation, and differentiation of endogenous stem cells.
All submitted solutions will be considered for the award. There will be a guaranteed award for at least one submitted solution. The total payout will be $15,000, with the possibility to distribute it amongst one or more Solvers, with at least one award being no smaller than $5,000 and no award being smaller than $1,000.
2. Additional application for Research Funding
In addition to consideration for the award for the submitted solutions, Solvers with appropriate qualifications and expertise having access to a suitable research laboratory and equipment can apply for research funding (“Research Funding”) to execute the research plan that is proposed in the solution. The selection of candidates for Research Funding will be conducted after completion of this Challenge
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