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我们对治疗克罗恩病和溃疡性结肠炎的新的机理和作用点感兴趣，这些可能包括，但不限于，接近病灶或调节菌群，代谢，遗传，后天产生的抗体。新治疗方法可能包括，但不限于，疫苗，基因治疗，和小分子化合物，而免疫抑制除外。理想的途径是先找到IBD发病新机理，再转化为一种治疗新的方法。具体如下：（https://www.innocentive.com/ar/challenge/9933446） Novel Treatment Approaches to Cure Inflammatory Bowel Diseases TAGS: Nature, Chemistry, Life Sciences, Ideation AWARD: $10,000 USD | DEADLINE: 2/16/15 | ACTIVE SOLVERS: 21 | POSTED: 12/16/14 The Seeker for this Challenge desires proposals describing potential approaches for curing Crohn’s disease and ulcerative colitis. The Seeker is interested in novel mechanisms of action that specifically address the pathogenesis of inflammatory bowel diseases (IBD). These may include, but are not limited to, approaches targeting or modulating the microbiota, metabolism, genetic, and epigenetic targets. Platforms may involve, but are not limited to, vaccines, gene therapy, and small molecule compounds. The Seeker is not interested in immunosuppression. Desirable approaches are specifically relevant to the pathogenesis of IBD and can be translated into a cure. This is an Ideation Challenge with a guaranteed award for at least one submitted solution. In addition to the Challenge award, the Seeker is open to establishing potential collaborations with the winning Solver(s) to further investigate proposed mechanisms with the eventual goal of developing a cure for IBD. Source: InnoCentive Challenge ID: 9933446 Challenge Overview The Seeker for this Challenge desires proposals for novel approaches that specifically address the causes of inflammatory bowel diseases (IBD) to enable the development of a cure. The Seeker is interested in unique ideas and new approaches (including gene delivery techniques), but is not interested in approaches that are simply common targets for various immunological conditions. That is, the approach must be specifically relevant to the pathogenesis of IBD and can be translated into a cure. This is an Ideation Challenge, which has   [更多]

要求在市面上流通并且涵盖药品基础信息。包括药品名称、厂家、包装规格、批准文号等内容。需要求购大批量的数据，量少暂不考虑。价格私聊，有资源者可以投稿联系，确定后付款。   [更多]

一、2，2-双二苯基膦-1，1-联萘的制备技术 技术难题：2，2-双二苯基膦-1，1-联萘的制备技术。解决技术难题要求达到的技术目标：纯度大于98%，外观为白色固体，总收率大于60%。   [更多]

由于个人精力原因，先急需转让一家医药连锁公司，公司有10多家门店，有160万库存，有完整的团队，接收可经营。   [更多]

这是高速度的药物API的片剂压制的一个主要问题。活性药物成分在压冲过程中的冲头被粘住而使片剂重量和剂量有所损失产生不同。我们寻找一种计算片剂压片机高速冲头上剂量和重量损失的模型，用以改进片剂工艺。具体请看下面英文描述：https://www.innocentive.com/ar/challenge/9933670 AWARD: $10,000 USD | DEADLINE: 2/22/15 | ACTIVE SOLVERS: 9 | POSTED: 1/23/15 Solid dosage forms (e.g. tablets) are the preferred dosage unit for pharmaceutical products. These units are produced by compressing particulate formulations. A major problem in the high speed pressing of tablet formulations of pharmaceutical API’s (Active Pharmaceutical Ingredient) is they sometimes tend to stick to the punches during the compression process. This causes weight loss defects in the tablets and thus costly manufacturing defects during production. A model is required to predict sticking of formulations in high speed presses to prevent losses in production. This is an Ideation Challenge with a guaranteed award for at least one submitted solution. Source: InnoCentive Challenge ID: 9933670 Challenge Overview Tablets are the main dosage form of choice for medicines. They have manufactured by compressing formulations which may consist of blended powders or granules. A major problem in the high speed pressing of tablet formulations of new medicines is they sometimes tend to stick to the surfaces of compaction equipment. This causes tablet weight and hence dose reduction and thus costly manufacturing defects during production. The phenomenon is frequently only observed on scale up due to the lengthy run times at large scale and is difficult to reproduce at smaller scales. New models (or partial model concepts) are required to improve the overall modeling of “stickiness” in tablet compression and predict the extent beforehand. Suggestions for improvements to either process route or equipment or to formulation ingredients to prevent sticking from the models are also desired. This is an Ideation Challenge, which has the following unique features: There is a guaranteed award. The awards will be   [更多]

标题：重金求购标题：重金求购兰地洛尔生产工艺 详细要求： 需求名称：兰地洛尔原料药工艺 具体要求：工艺要能达到实验室中试规模，各步中间体的质量控制及成品的质量控制标准 要求时间：请在2022年2月之前 交稿方式：直接点击交稿在线交稿就是了，我会每天过来看的，谢谢各位药智的战友们   [更多]

我司急需以下三种原料药的工艺包 1. Amoxiciillin 阿莫西林 羟氨苄青霉素 2. Metformin 二甲双胍 3.Paracetamol 扑热息痛 对乙酰氨基酚 详细信息请与平台客服联系。   [更多]

需要化合物 cas：1204-23-5（3,4-dihydro-7-methoxy-1-methyl-2(1H)-naphthalenone） ，截止日期为2015年2月28日，纯度大于95%，自己报价 ；   [更多]

需要条形码数据对应药品的基本信息   [更多]

1、通过广东省药品批发企业GSP认证的药品批发公司 2、财务干净，应收款应付款最好没有，如果有应能合理解释 3、无历史欠税 4、可以配合尽职调查   [更多]