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2010年版《中国药典》及增补是新中国成立60年来组织编制的第九版药典，注重创新与发展，全面提升了我国药物质量控制的要求与水准，是国家药品标准体系的核心。作为色谱行业的领导者，沃特世(Waters?)公司长期以来得到广大制药行业用户的支持与厚爱，其提供的优质色谱柱及消耗品为药品质量控制提供了强有力的保障和技术支撑。为答谢广大用户对沃特世公司的支持与帮助、进一步增进用户之间的交流，特向广大沃特世色谱柱制药领域用户征集2010版中国药典高效液相色谱图，并将汇编成册回馈客户。 一、征集对象 沃特世色谱柱制药领域用户 二、征集要求 1、所用的Waters色谱柱规格型号、色谱条件完整准确;图谱真实、清晰，基线稳定，目标成分峰型良好，分离度、保留时间、理论塔板数符合要求。 三、评审与奖励 1、将邀请专家为本次征集活动进行评审，所有被录用图谱的作者均将获得特制U盘一个。 2、活动将选出前十名对图谱征集贡献最大的单位或个人成为沃特世VIP客户，将给予更低的优惠折扣。 四、征集时间及联系方式 征集时间：2013年1月1日-2013年5月31日 Word文件请电邮至info_chemistry@waters.com(请将附件粘贴到邮件中) 联系人：Anne 联系电话：021-61562630   [更多]

寻找一种可以代替粘结剂（胶水）粘结聚合材料的方法，聚合材料如：织物，橡胶，泡沫或胶片。粘合效果必须是长久有效的，并且优于粘合剂如：性价比，快速粘合时间。 投标截止时期2016年5月30日, 投标网址：https://www.innocentive.com/ar/challenge/9933860 Bonding of Polymeric Materials without Adhesives TAGS:CChemistry \\ Physical Sciences \\ Engineering \\ Design \\ Royal Society of Chemistry AWARD: $10,000 USD | DEADLINE: 5/30/16 | ACTIVE SOLVERS: 123 | POSTED: 4/28/16 The Seeker is looking for alternative methods to bond specific polymeric materials together other than adhesives. These polymeric materials can be in many forms including fabrics, rubber, foams and films. The bond must be durable and offer advantages over adhesives like cost and time savings. This Theoretical Challenge requires only a written proposal. Source: InnoCentive Challenge ID: 9933860 Sign Agreement For This Challenge By electronically signing the agreement below, you are indicating your intention to view the details of this specific InnoCentive Challenge. Viewing the Challenge Details does not obligate you to perform any work on this challenge. Print this Agreement for your records InnoCentive Theoretical (IP Rights Transfer) Challenge-Specific Agreement Please Read This Carefully! You and InnoCentive are agreeing to a Challenge-Specific Solver Agreement for this particular InnoCentive Challenge only, as permitted in the Terms of Use. The Seeker for this InnoCentive Challenge has required that you accept these special terms, so please take the time to understand them. If you click \\"I agree\\" and proceed to the Project Room for this InnoCentive Challenge, this Challenge-Specific Agreement (\\"CSA\\") will be a valid and binding agreement for all purposes relating to this InnoCentive Challenge and in addition to your agreement to abide by the Terms of Use when you registered as a Solver. Please print and keep a copy of this CSA. No provisions you may have agreed to that are specific to any other individual InnoCentive Challenge will apply. 1. Your   [更多]

再生药的发展领域，主要集中在修复和取代受损细胞组织或病源组织。干细胞有自我修复功能。胚胎干细胞可以开发成身体内任何形式的细胞组织，成体干细胞的功能是维护或修复身体内部的细胞。Boiheringer Ingelheim的寻找目标是：调动，刺激，分化新的内源性干细胞分子结构的途径。 投标截止时期2016年6月24日, 投标网址：https://www.innocentive.com/ar/challenge/9933855 原文 Mobilization, Stimulation, and Differentiation of Endogenous Stem Cells TAGS: Chemistry, Royal Society of Chemistry, Life Sciences, Ideation AWARD: $15,000 USD | DEADLINE: 6/24/16 | ACTIVE SOLVERS: 51 | POSTED: 4/25/16 1. The Challenge and qualification for the award During early development, embryonic stem cells are undifferentiated cells that can be stimulated to proliferate and develop into all different cell types. In adults, these endogenous cells are found in tissues and they can divide either to replenish the stem cell population or differentiate into specialized cells of the tissue in which they reside. These adult stem cells function as an internal maintenance or repair system, so it would be beneficial to be able to direct and enhance this regenerative capacity. Therefore, Boehringer Ingelheim (the Seeker) desires the identification of new molecular mechanisms and pathways involved in mobilization, stimulation, and differentiation of endogenous stem cells. All submitted solutions will be considered for the award. There will be a guaranteed award for at least one submitted solution. The total payout will be $15,000, with the possibility to distribute it amongst one or more Solvers, with at least one award being no smaller than $5,000 and no award being smaller than $1,000. 2. Additional application for Research Funding In addition to consideration for the award for the submitted solutions, Solvers with appropriate qualifications and expertise having access to a suitable research laboratory and equipment can apply for research funding (“Research Funding”) to execute the research plan that is proposed in the solution. The selection of candidates for Research Funding will be conducted after completion of this Challenge   [更多]

为健康动物做明显标记的染料或颜料，通常有以下2种限制： 1. 染料往往是活性的，因此不容易褪色，并有强烈的产品活性成分。 2. 颜料活性低，不粘附皮肤，所以容易被清洗。 目标要求是研发一种能在动物体上染色的环保材料（如：染料，颜料或其他） 或者一种配方能够达到相同效果。 投标截止时期2016年5月29日, 投标网址https://www.innocentive.com/ar/challenge/9933850 原文 Challenge Overview The Seeker to this Challenge has a cleaning product for animal hygiene to which the Seeker intends to add the capability to stain skin with a clear, visible mark. Various dyes and pigments exist with the potential to provide this feature, however two limitations have been found: • Dyes tend to be reactive, hence not staining and consuming the active ingredient of the product. • Pigments are less reactive, do not adhere to skin, and are therefore easily washed out. The Challenge is to develop a highly colored version of the cleaning product adding to it the ability to stain animal skin. Hence, the Seeker is looking for ideas for ingredients (dyes, pigments, or others) and/or formulations that can overcome the above identified limitations and achieve this effect. This is a Theoretical Challenge that requires only a written proposal to be submitted. The Challenge award will be contingent upon theoretical evaluation of the proposal by the Seeker. Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on May 29, 2016. Late submissions may not be considered. To receive an award, the Solvers will have to transfer to the Seeker their exclusive Intellectual Property (IP) rightsto the solution.   [更多]

为进一步加强食品药品安全宣传教育，广泛普及饮食用药安全常识，全面提升社会公众食品药品安全知识水平，大力营造全社会共同关注、共同参与食品药品安全工作的良好氛围，省食品药品监督管理局即日起举办“吉林省首届食品药品科普创意大赛”，面向全社会征集食品药品科普创意作品。具体方案如下： 一、活动主题 食美药安，健康相伴 二、活动时间 2016年5月12日-2016年6月30日 三、组织机构 主办单位：吉林省食品药品监督管理局 承办单位：吉林省凤凰智业影视有限公司 媒体支持：吉林日报、吉林电视台、吉林人民广播电台、新文化报、城市晚报、东亚经贸新闻、手机报、新华网等。 四、 作品要求 （一） 作品主题 1、宣传食品、药品、保健食品、化妆品和医疗器械（“四品一械”）方面的法律法规和标准制度； 2、普及饮食用药安全常识，倡导科学理性健康消费观念； 3、宣扬“尚德守法”理念，增强食品药品生产经营者诚信守法的责任意识； 4、传播食品药品安全社会共治理念，鼓励社会各界通过12331举报食品药品违法违规行为，同心携手维护食品药品安全。 （二）作品类型 1、平面设计类 格式：.TIFF、.JPG 分辨率：500dpi 尺寸：210MM（宽）X297MM（高） 色彩模式：RGB 大小：单个文件不大于5MB 2、视频类 格式：不限形式，视频拍摄、FLASH、动画制作均可。 时长：30秒以上，2分钟以内。 分辨率：标清视频为720*576；高清视频为1920*1080。 大小：单个文件不大于100MB （三）内容要求 1、参与者可选择一个或多个食品药品安全主题进行创作，要求作品形象生动、通俗易懂、积极健康，具有一定科普功能。 2、参赛作品应观点正确，符合国家法律、法规、规章和社会道德规范，体现公共利益。 3、参赛作品要求原创，凡涉及抄袭、模仿等问题的作品不得参赛。作品的著作权、与作品相关的肖像权、名誉权等法律问题，由参赛者自行解决并承担责任。 五、参赛方式 （一）参赛报名 为及时掌握参赛情况，设置报名环节。登陆省局门户网站，进入大赛报名页，网上报名。 （二）作品报送 填写《参赛作品登记表》连同参赛作品一并发送至指定邮箱。在邮件主题上标注“科普创意大赛-类别-姓名”，如：视觉创意大赛-平面设计类-张三。 参赛作品不予退还，参赛者自留底稿。 六、奖项设置 平面设计类、视频类分别设置一、二、三等奖和优秀作品奖。 七、步骤安排 （一）前期推介 以30秒短视频及文字或图片形式在新闻媒体上对活动进行宣传，同时在《吉林食品药品安全报》、吉林省食品药品监督管理局门户网站网及微信公众平台推介。 （二）作品征集 收集整理参赛作品，并在门户网站展示。 （三）作品遴选 省局组织专家，围绕作品主题，按照公平、公正、公开的原则，对所有参赛作品进行审核，遴选出优秀作品。遴选标准： 1、创意精巧，主题鲜明； 2、时效性强，突出正能量； 3、具有视觉冲击力，适宜传播。 （四）结果公布 活动结束后，在省食品药品监督管理局网站和微信平台上公布获奖作品名单。 本次活动对征集作品具有合法使用权，作品将在指定媒体、网站及相关活动中公开展播或刊登，不另付稿酬。   [更多]

要全国的联系方式，其他方面的个人资料。欢迎来稿，需求量大！   [更多]

阻塞性睡眠呼吸暂停（简称OSA），在美国影响数百万人和其他国家更多的人。幸运的是，在非手术治疗中，存在一个有效的持续气道正压通气装置（简称CPAP），可用在患者睡觉时。不幸的是，通过改进设备和教育患者的努力，患有OSA的患者使用 CPAP仍然在40-50%的范围。 我们寻求增加和坚持使用CPAP治疗OSA的创新解决方案。提交的解决方案可以采取各种各样的方法来解决的患者在心理上，身体上，或不适应CPAP等问题。 提交方案请在：https://www.innocentive.com/ar/challenge/9933907　上投稿。 截止日期：2016年9月21日   [更多]

“科技每年都会见证一些神奇的真理和制造出令人眼花缭乱的东西,如吴雨霏穆利斯《创新的聚合酶链式反应》。 不幸的是，他们中的大多数被淘汰出局。而聚合酶链式反应则预示着基因组的革命. 这是一项关于思维的挑战，这项任务要求挑战者来概述制药行业需要采取哪些创新，来适应这优胜劣汰的游戏规则。挑战者不需要发表明确的解决方案，你只需要清楚的描述已经存在的，可能会成为下一个制药趋势的大事。这将有助于制药行业寻找明天的药物，生产新药。 What Disruptive Innovations Does Pharma Need To Discover Tomorrow’s Drugs? AWARD: $5,000 USD | DEADLINE: 10/15/12 | ACTIVE SOLVERS: 220 | POSTED: 9/14/12 Source: InnoCentive Challenge ID: 9932826 Type: Ideation Detailed Description & Requirements Background Productivity in drug discovery & development – the number of new drugs reaching patients – has been declining. At the same time, R&D spending has been increasing. Industry experts calculate the mean R&D spend per new drug on the market is $4-11 billion dollars. 2012 Forbes Article: The Truly Staggering Cost of Inventing New Drugs The Problem Various factors contribute to this high development cost. The most prominent is the high rate of attrition (failure) on drug like compounds as they pass through the drug development process. For every 10,000 compounds that appear interesting during basic research, 1 may reach market as an approved drug. Causes of compounds not progressing include: Lack of efficacy or potency Unfavorable pharmacology/pharmacodynamics Toxicity or safety Increasing regulatory stringency in approving drugs for clinical trial and for market Increasing emphasis on stratification of patient populations for administration of drugs (personalized medicine) Factors contributing to these causes include, but are not limited to: Assay systems and platforms that poorly replicate drug effects in humans Lack of new therapeutic drug targets being identified e.g. phenotypic screening data is difficult to convert into new molecular targets Animal experimental data, too, poorly predicts effects in humans / translational medicine Lack of good validated biomarkers to measure disease states or predict   [更多]