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专利申请号：201620283879.X，实用新型，处于授权未交费状态。   [更多]

主要是求购针剂和乳膏剂批文   [更多]

标题：求 维生素D滴剂或维生素D2软胶囊一致性评价 详细要求： 需求名称：维生素D滴剂或维生素D2软胶囊一致性评价专家 具体要求：寻找一个维生素D滴剂或维生素D2软胶囊一致性评价方面的专家或团队，要求擅长一致性评价相关工作和法规，有维生素D的研究背景，能够满足一致性评价方面的要求，有一致性评价成功案例的优先。 交稿方式：直接点击交稿在线交稿就是了，我会每天过来看的，谢谢各位   [更多]

痤疮(粉刺)是一种慢性炎症性皮肤病，通常开始于青春期，其特点是在脸上的青春痘，也会出现在颈部和身体上。发作的痤疮往往可以成功地通过药物治疗和完善的日常护理方案调整皮肤类型。轻度和中低度痤疮用局部治疗方法，而中度至重度痤疮患者需要口服治疗。患者可能会遇到不必要的副作用，如皮肤刺激，甚至抗生素耐药性。未得到治疗的瘢点或控制不佳会导致永久性的疤痕、情感上的痛苦，心理焦虑和抑郁等问题。痤疮的医疗需求仍然未满足，特别是对那些不对应标准的护理疗法的人。因此寻找新的治疗方法，以改善痤疮患者的生活。 悬赏截止时间为2016年8月31日下午11:59止（美国东部时间）。 投标网址：https://www.innocentive.com/ar/challenge/9933873?challenge=9933873   [更多]

通常情况下，清洁假牙污渍，给假牙消毒是一系列费力又乏味的过程，如：取下假牙，用水冲洗，准备清洁剂，把假牙浸泡在清洁剂中，洗刷假牙，等等。 寻求一种高效清洁技术，能简化上述中一些复杂的过程，从而达到更高效的用户体验。如：把假牙放到清洁剂中，直接达到清洁的作用。 悬赏截止日期：2016年6月19日 投标网址：https://www.innocentive.com/ar/challenge/9933825 原文： Challenge Overview Maintaining dentures clean, free from stains and disinfected, requires a number of laborious and tedious procedures when they are out of the mouth. Removing the denture, rinsing the denture, preparing a cleaning solution, soaking and brushing the denture, are all tasks that have to be repeatedly performed and that consumers find cumbersome. A great improvement for consumer experience would be to have a highly efficient cleanser that would make denture care easier. Imagine for example a situation where it would be as simple as removing the denture and immersing it for a few seconds in a liquid solution – this would be a dream scenario. Therefore, the Seeker is seeking for novel alternative cleanser technologies that are be more consumer-friendly but still highly efficient. This is a Theoretical Challenge that requires only a written proposal to be submitted. The Challenge award will be contingent upon theoretical evaluation of the proposal by the Seeker. To receive an award, the Solvers will have to transfer to the Seeker their exclusive Intellectual Property (IP) rights to the solution. However, the Seeker will be willing to consider a licensing agreement for a partial award if exclusive IP cannot be transferred by the Solver. Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on June 19, 2016. Late submissions may not be considered. IMPORTANT NOTE: The Seeker for this Challenge requires additional Solver verification and due diligence. Please read carefully the respective sections in the Challenge Specific Agreement for further information or use your Project Room to ask a question.   [更多]

从成本效益角度出发，寻找一种可以大规模生产天然叶醇的制造技术。需要提供出参考资料，实验数据和样品。参考资料中需要列出技术需求，详细描述的实验数据，同时需要提供原材料的样品。 转让知识产权后，将收到赏金。 悬赏截止日期：2016年8月18日 投标网址：https://www.innocentive.com/ar/projectRoom/index?challenge=9933857 Challenge Overview Cis-3-hexenol (leaf alcohol) is a fragrant compound naturally produced by plants. Its characteristic odor has made it a highly successful natural green compound in the flavor and fragrance industry. High demand for this ingredient makes it a constant challenge for the industry to develop processes that can, at a low production cost per kg, allow for the consistent, sustainable and high-quality manufacturing of multi tones of this product. Hence, the Seeker is challenging scientists and technologists to come up with whole processes (from production to downstream processing) to meet this need. Please read the Detailed Description section to learn about the technical requirements that your proposed process should meet. The submission to the Challenge should include the following: 1. The detailed description of the proposed Solution addressing specific Technical Requirements presented in the Detailed Description of the Challenge. This description should be accompanied by a well-articulated rationale supported by literature/patent precedents. 2. Experimental data obtained as outlined in the Detailed Description of the Challenge (and/or delivery of a material sample of the product if requested by the Seeker). The Challenge award is contingent upon theoretical evaluation and experimental validation on a 15 L pilot scale of the submitted Solutions by the Seeker. To receive an award, the Solvers will have to transfer to the Seeker their exclusive Intellectual Property (IP) rights to the solution. Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on August 18, 2016. Late submissions will not be considered.   [更多]

控制体内血糖水平是成功治疗许多疾病的关键，如糖尿病。 因此， Novo Nordisk公司正在寻找新的小分子，它可以于D-葡萄糖的生理集合密切结合 (持续的取代，Kd，低毫摩尔范围) 悬赏须提交概念性实验数据报告和样品，Novo Nordisk公司将决定最终得奖者，并颁发起始奖金200000美金。 另外Novo Nordisk公司将提议基于里程碑式的合约，如果分子式在未来悬赏中得到成功研发，将会得到二次奖项。 悬赏截止时期2017年1月9日, 投标网址：https://www.innocentive.com/ar/projectRoom/index?challenge=9933823 原文: Novo Nordisk Challenge: Design and Synthesis of a Small Molecule Glucose Binder TAGS: Chemistry, Life Sciences, Royal Society of Chemistry, RTP AWARD: $200,000 USD | DEADLINE: 1/09/17 | ACTIVE SOLVERS: 145 | POSTED: 3/30/16 The control of glucose levels in the body is key for successful treatment of many disease states such as diabetes. Hence, Novo Nordisk is looking for novel small molecules that can bind with affinities matching the physiological concentrations of D-glucose (displacement constant, Kd, in the low millimolar range). This is a Reduction-to-Practice Challenge that requires written documentation, experimental proof-of-concept data, and sample delivery. Additionally, the Challenge has the following unique features.Please read carefully the Challenge-Specific Agreement. • Solvers are asked to prepare the compound and perform binding affinity assays to glucose in aqueous solution under conditions described in the Challenge Description. The compounds must also be supplied to Novo Nordisk in sufficient amounts to reproduce the results. Upon experimental validation of the results, Novo Nordisk will make an award (‘Initial Transfer Fee’) of $200,000 to the best solution as solely determined by the Seeker, according to the Challenge requirements. The Awarded Solver grants Novo Nordisk an exclusive license under the terms described in the Challenge-Specific Agreement. • Additionally, Novo Nordisk will offer a milestone-based agreement to the Solver, establishing the terms of payment of anadditional award (‘Secondary Award’), should the small molecule be successful in its development post-Challenge(‘Second Evaluation Period’), in exchange   [更多]

Boehringer Ingelheim公司寻找一种有机小分子，能够安全使用，没有生物活性，或非常温和的生物活性，能够显示细胞的渗透性，并且在长期口服的情况下能够达到高血药浓度。 有机小分子常见于：药物化学，内科医师，配方科学（盖仑制剂），药剂学，药理学等领域。 有机小分子不常见于 ：动物医疗，农业科学，食物化学，营养学，化妆品，或其他等领域。 投标截止时期2016年6月26日, 投标网址：https://www.innocentive.com/ar/projectRoom/index?challenge=9933854 Seeking Safe Drug-like Small Organic Molecules for Human Use with Negligible Biological Effects TAGS: Chemistry, Life Sciences, Food/Agriculture, Royal Society of Chemistry, Ideation AWARD: $20,000 USD | DEADLINE: 6/26/16 | ACTIVE SOLVERS: 106 | POSTED: 4/27/16 Boehringer Ingelheim (The Seeker) is interested in small organic molecules that are safe for human use, show no, or very mild, biological activity, display cell permeability, and achieve high concentrations (µM) in the plasma when chronically administered via the oral route. This is an Ideation Challenge with a guaranteed award for at least one submitted solution. Source: InnoCentive Challenge ID: 9933854 Sign Agreement For This Challenge By electronically signing the agreement below, you are indicating your intention to view the details of this specific InnoCentive Challenge. Viewing the Challenge Details does not obligate you to perform any work on this challenge. Print this Agreement for your records InnoCentive Ideation Challenge-Specific Agreement Please Read This Carefully! You and InnoCentive are agreeing to a Challenge-Specific Solver Agreement for this particular InnoCentive Ideation Challenge only. The Seeker for this InnoCentive Challenge has required that you accept these special terms, so please take the time to understand them. If you click \\"I agree\\" and proceed to the Project Room for this InnoCentive Challenge, this Challenge-Specific Agreement (\\"CSA\\") will be a valid and binding agreement between you and InnoCentive and in addition to the existing Terms of Use for all purposes relating to this InnoCentive Challenge. Please print and keep a copy of this CSA. No provisions you may have   [更多]

碳酸氢钠是预防初期牙龈炎的一种活性成分，它存在各种牙膏中。当碳酸氢钠高浓度存在于牙膏中，非常咸的味道会令人不愉快。 悬赏任务是，在高浓度碳酸氢钠牙膏中，寻找一种掩盖咸味道的技术。 悬赏截止时期2016年7月31日, 投标网址：https://www.innocentive.com/ar/projectRoom/index?challenge=9933826 Masking Salty Taste TAGS: Royal Society of Chemistry, Chemistry, Food/Agriculture, Life Sciences, RTP AWARD: See details | DEADLINE: 7/31/16 | ACTIVE SOLVERS: 94 | POSTED: 5/05/16 Sodium bicarbonate is a salt that is used as an ingredient in various products for many applications across various industries. It has a particularly strong salty taste, hence in applications where it is ingested, the salty flavour is pronounced. That is the case in toothpastes, where the beneficial gum protection effect that sodium bicarbonate delivers is overshadowed by the unpleasant salty taste that is felt by consumers, making such toothpastes unpopular. Do you have a technology that can mask the salty taste and make it imperceptible in toothpastes? This is a Reduction-to-Practice Challenge that requires written documentation, experimental proof-of-concept data, and, if requested by the Seeker, sample delivery. Source: InnoCentive Challenge ID: 9933826 Sign Agreement For This Challenge By electronically signing the agreement below, you are indicating your intention to view the details of this specific InnoCentive Challenge. Viewing the Challenge Details does not obligate you to perform any work on this challenge. Print this Agreement for your records InnoCentive RTP Challenge-Specific Agreement Please Read This Carefully! You and InnoCentive are agreeing to a Challenge-Specific Solver Agreement for this particular InnoCentive Challenge only, as permitted in the Terms of Use. The Seeker for this InnoCentive Challenge has required that you accept these special terms, so please take the time to understand them. If you click \\"I agree\\" and proceed to the Project Room for this InnoCentive Challenge, this Challenge-Specific Agreement (\\"CSA\\") will be a valid and   [更多]

通常粘合假牙的化学物会从边缘过量留出，造成的在口中含有化学味道，同时伴随红肿等不良性。寻求一种取代现有的粘合技术，从而改善顾客体验的一种新的技术。 投标截止时期2016年6月5日, 投标网址：https://www.innocentive.com/ar/challenge/9933824 Seeking New Technologies for Denture Adhesives TAGS: Chemistry, Physical Sciences, Life Sciences, Engineering/Design, Theoretical-IP Transfer AWARD: $20,000 USD | DEADLINE: 6/05/16 | ACTIVE SOLVERS: 50 | POSTED: 5/05/16 The use of denture adhesives often comes with an unpleasant sensorial experience for the user, for example, an unpleasant chemical taste, “swelling” and over-flow of the product (oozing) from the edges of the denture and a grainy texture in the mouth. The Seeker for this Challenge is looking to improve this experience for consumers, hence is seeking novel alternative adhesive technologies that can better the sensorial experience without compromising holding performance. This Challenge requires only a written proposal. Source: InnoCentive Challenge ID: 9933824 Sign Agreement For This Challenge By electronically signing the agreement below, you are indicating your intention to view the details of this specific InnoCentive Challenge. Viewing the Challenge Details does not obligate you to perform any work on this challenge. Print this Agreement for your records InnoCentive Theoretical (IP Rights Transfer) Challenge-Specific Agreement Please Read This Carefully! You and InnoCentive are agreeing to a Challenge-Specific Solver Agreement for this particular InnoCentive Challenge only, as permitted in the Terms of Use. The Seeker for this InnoCentive Challenge has required that you accept these special terms, so please take the time to understand them. If you click \\"I agree\\" and proceed to the Project Room for this InnoCentive Challenge, this Challenge-Specific Agreement (\\"CSA\\") will be a valid and binding agreement for all purposes relating to this InnoCentive Challenge and in addition to your agreement to abide by the Terms of Use when you registered as a Solver.   [更多]