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这是一项关于寻找材料加工技术的任务，要求是要用纳米团簇生产含能材料，这个技术的重点要是在一个可控的过程中进行，要有稳定的空气和粒子率增加一致。 这个任务需要提交一份书面的建议书 Energetic Core-Shell Nanocluster Production AWARD: $20,000 USD | DEADLINE: 11/19/12 | ACTIVE SOLVERS: 116 | POSTED: 9/19/12 Source: InnoCentive Challenge ID: 9932739 Type: Theoretical-licensing Detailed Description & Requirements Background Core-shell nanoclusters are groups of atoms of usually 2 materials in an arrangement such that one material, in the center, is the “core” of atoms which is coated with atoms of another material or the “shell”. These clusters contain from 10’s to millions of atoms and aggregates are in the nanometer range (~5 to 1000 nm). An example would be a core of Fe atoms and a shell of Au atoms. The Fe would not be stable as it would oxidize quite rapidly on its own, but the gold shell protects it from oxidation, yet the small clusters still exhibit magnetic behavior. This is the most simplistic core-shell and there are many different arrangements with multiple materials and multiple shells and the Solvers can look at the references attached for more information. Nanoclusters are unique as they exhibit properties different from bulk materials which are many times cluster size dependent. Of particular interest are highly energetic materials such as mixtures of metals and metal oxides. As nanoclusters, these materials have increased reactivity, because mass transport is removed as a barrier between fuel and oxidizer (i.e. all atoms are in intimate contact). Using the classic thermite reaction, an Al core of atoms could be coated with Fe Oxide which would protect the Al from oxidation. When ignited as nanoclusters the reaction rate would be increased over the bulk materials. The Challenge The Seeker is interested in material processing technologies for the production or fabrication of nano-scale core-shell cluster energetic materials with particle diameters between 5 and 25 nm. This process has been done in   [更多]

求购三黄片中黄芩浸膏的制备工艺 应按照2010版药典中三黄片质量标准项下要求工艺进行，并符合其质量标准。   [更多]

求购5-硝基糠醛二乙酯合成工艺，要求收率超过80%，勿复制粘贴网上内容，有意者可寻求合作   [更多]

求购吉美嘧啶的对照原料药，国外原研的最好，国内3家有批文的厂家的也行。   [更多]

雷贝拉唑钠小试工艺和少量合格样品，原料药合成的   [更多]

连翘叶提取物要求：水分：4%以下，连翘苷含量：5.0%以上，3%的连翘叶提取物水溶液灯光下观察澄清透明，能过0.45的微膜。   [更多]

PXE国际关于弹性假黄瘤(PXE)的研究团队，对其的病因提出了现有的两种假设：积极的循环代谢产物或者组织特异性功能障碍。任务要求提供数据来求证这两种假设或其中之一。根据各地的发病机制进行实验，进一步了解PXE的病因。 这项任务保证至少会奖励一名挑战者，并且，除了任务奖金之外，PXE国际还将对中标者给予PXE的研究经费资助。 征稿件请直接上传网址：https://www.innocentive.com PXE – Evaluating Hypotheses and Suggesting Experiments for a Rare Disease TAGS: Computer Science/Information Technology, Chemistry, Global Health, Nature, Public Good, Life Sciences, Ideation AWARD: $7,000 USD | DEADLINE: 11/30/12 | ACTIVE SOLVERS: 38 | POSTED: 10/31/12 The Seeker, PXE International, the primary group responsible for funding PXE research, presents two existing hypotheses (an active circulating metabolite(s) or a tissue-specific dysfunction) for the rare disease Pseudoxanthoma Elasticum (PXE). The Seeker requests that Solvers present evidence favoring one of the two hypotheses, then provide additional experiments to conduct to further knowledge around the disease mechanism. This is an Ideation Challenge with a guaranteed award for at least one submitted solution. In addition to the Challenge award, PXE International will also assist finalists in efforts to obtain funding for PXE-related research. Detailed Description & Requirements INTRODUCTION TO PXE Pseudoxanthoma Elasticum (PXE) is a recessive genetic disorder with signs and symptoms that mimic many aspects of the normal aging process, but at a much younger age (when people are roughly between 10 and 20 years old). Specifically, the disease is characterized by fragmentation and mineralization of elastic fibers in certain tissues. Some of the more common symptoms, in general order that they occur, are: Wet-type macular degeneration Skin wrinkling Calcification of blood vessels Cardiovascular disease PXE is a rare disease with an estimated patient population of 12,000 people. Given the small number of people with the disease, it has not been the subject of research by for-profit pharmaceutical and biotech companies.   [更多]

　　求购孟鲁司特钠大生产合成工艺，如工艺真实，重复性好，现金支付酬金。   [更多]

现我公司需要生产一些软袋样品，希望能找一个公司的软袋输液生产线代为加工生产，加工费价格好商量，如果能介绍成功，给予1000元介绍费。 联系QQ：1620567963   [更多]

摘要： 这项任务是寻找一种新的配方，合成除虫菊酯缓释制剂。 要求改变其生物活性化合物的挥发，使其的生物活性超过一年。这项配方必须要有足够的稳定性，即使是在热带环境中放几年也不受影响。并且所得的制剂在跟水稀释后能喷洒或涂刷在表面。要求这个配方必须使用常用的材料和国家最先进的制造工艺，并且对人体和环境是安全的。 这项任务需要提交一份详细的书面报告。 具体要求： Sustained Release Formulation for Synthetic Pyrethroids TAGS: Food/Agriculture, Chemistry, Physical Sciences, Theoretical-IP Transfer AWARD: $25,000 USD | DEADLINE: 12/16/12 | ACTIVE SOLVERS: 10 | POSTED: 10/16/12 The Seeker is looking for a novel formulation that modifies the volatility of a biologically active compound to give a product with activity of more than one year. The formulation should be stable for several years of storage even under tropical conditions. The resulting formulation should be able to be applied by spraying or by brushing etc. after dilution with water on many surfaces. The Seeker requires that the formulation technique must use commonly available materials and state of the art manufacturing process, as well as be safe for humans and the environment. This Challenge requires only a written proposal. Sustained Release Formulation for Synthetic Pyrethroids Detailed Description & Requirements INTRODUCTION The Seeker is keenly interested in finding a “new and novel” approach to formulation that will stabilize a volatile synthetic bioactive, for a full year after application via sprayed or brushed-on use scenarios, yet protected from its typical routes of decomposition. The formulation must be considered safe for humans and the environment, and it must be cost-effective to manufacture from commodity-type materials using state-of-the-art manufacturing processes. DETAILS OF COMPOUND TO BE FORMULATED The active the seeker is interested in belongs to the chemical class of synthetic pyrethroids (http://en.wikipedia.org/wiki/Pyrethrin). It has a molecular weight of approx. 400, a vapor pressure of about 1mPa at 25°C, a very poor solubility in water but high in non-polar media. Types of   [更多]