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从成本效益角度出发，寻找一种可以大规模生产天然叶醇的制造技术。需要提供出参考资料，实验数据和样品。参考资料中需要列出技术需求，详细描述的实验数据，同时需要提供原材料的样品。 转让知识产权后，将收到赏金。 悬赏截止日期：2016年8月18日 投标网址：https://www.innocentive.com/ar/projectRoom/index?challenge=9933857 Challenge Overview Cis-3-hexenol (leaf alcohol) is a fragrant compound naturally produced by plants. Its characteristic odor has made it a highly successful natural green compound in the flavor and fragrance industry. High demand for this ingredient makes it a constant challenge for the industry to develop processes that can, at a low production cost per kg, allow for the consistent, sustainable and high-quality manufacturing of multi tones of this product. Hence, the Seeker is challenging scientists and technologists to come up with whole processes (from production to downstream processing) to meet this need. Please read the Detailed Description section to learn about the technical requirements that your proposed process should meet. The submission to the Challenge should include the following: 1. The detailed description of the proposed Solution addressing specific Technical Requirements presented in the Detailed Description of the Challenge. This description should be accompanied by a well-articulated rationale supported by literature/patent precedents. 2. Experimental data obtained as outlined in the Detailed Description of the Challenge (and/or delivery of a material sample of the product if requested by the Seeker). The Challenge award is contingent upon theoretical evaluation and experimental validation on a 15 L pilot scale of the submitted Solutions by the Seeker. To receive an award, the Solvers will have to transfer to the Seeker their exclusive Intellectual Property (IP) rights to the solution. Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on August 18, 2016. Late submissions will not be considered.   [更多]

碳酸氢钠是预防初期牙龈炎的一种活性成分，它存在各种牙膏中。当碳酸氢钠高浓度存在于牙膏中，非常咸的味道会令人不愉快。 悬赏任务是，在高浓度碳酸氢钠牙膏中，寻找一种掩盖咸味道的技术。 悬赏截止时期2016年7月31日, 投标网址：https://www.innocentive.com/ar/projectRoom/index?challenge=9933826 Masking Salty Taste TAGS: Royal Society of Chemistry, Chemistry, Food/Agriculture, Life Sciences, RTP AWARD: See details | DEADLINE: 7/31/16 | ACTIVE SOLVERS: 94 | POSTED: 5/05/16 Sodium bicarbonate is a salt that is used as an ingredient in various products for many applications across various industries. It has a particularly strong salty taste, hence in applications where it is ingested, the salty flavour is pronounced. That is the case in toothpastes, where the beneficial gum protection effect that sodium bicarbonate delivers is overshadowed by the unpleasant salty taste that is felt by consumers, making such toothpastes unpopular. Do you have a technology that can mask the salty taste and make it imperceptible in toothpastes? This is a Reduction-to-Practice Challenge that requires written documentation, experimental proof-of-concept data, and, if requested by the Seeker, sample delivery. Source: InnoCentive Challenge ID: 9933826 Sign Agreement For This Challenge By electronically signing the agreement below, you are indicating your intention to view the details of this specific InnoCentive Challenge. Viewing the Challenge Details does not obligate you to perform any work on this challenge. Print this Agreement for your records InnoCentive RTP Challenge-Specific Agreement Please Read This Carefully! You and InnoCentive are agreeing to a Challenge-Specific Solver Agreement for this particular InnoCentive Challenge only, as permitted in the Terms of Use. The Seeker for this InnoCentive Challenge has required that you accept these special terms, so please take the time to understand them. If you click \\"I agree\\" and proceed to the Project Room for this InnoCentive Challenge, this Challenge-Specific Agreement (\\"CSA\\") will be a valid and   [更多]

通常粘合假牙的化学物会从边缘过量留出，造成的在口中含有化学味道，同时伴随红肿等不良性。寻求一种取代现有的粘合技术，从而改善顾客体验的一种新的技术。 投标截止时期2016年6月5日, 投标网址：https://www.innocentive.com/ar/challenge/9933824 Seeking New Technologies for Denture Adhesives TAGS: Chemistry, Physical Sciences, Life Sciences, Engineering/Design, Theoretical-IP Transfer AWARD: $20,000 USD | DEADLINE: 6/05/16 | ACTIVE SOLVERS: 50 | POSTED: 5/05/16 The use of denture adhesives often comes with an unpleasant sensorial experience for the user, for example, an unpleasant chemical taste, “swelling” and over-flow of the product (oozing) from the edges of the denture and a grainy texture in the mouth. The Seeker for this Challenge is looking to improve this experience for consumers, hence is seeking novel alternative adhesive technologies that can better the sensorial experience without compromising holding performance. This Challenge requires only a written proposal. Source: InnoCentive Challenge ID: 9933824 Sign Agreement For This Challenge By electronically signing the agreement below, you are indicating your intention to view the details of this specific InnoCentive Challenge. Viewing the Challenge Details does not obligate you to perform any work on this challenge. Print this Agreement for your records InnoCentive Theoretical (IP Rights Transfer) Challenge-Specific Agreement Please Read This Carefully! You and InnoCentive are agreeing to a Challenge-Specific Solver Agreement for this particular InnoCentive Challenge only, as permitted in the Terms of Use. The Seeker for this InnoCentive Challenge has required that you accept these special terms, so please take the time to understand them. If you click \\"I agree\\" and proceed to the Project Room for this InnoCentive Challenge, this Challenge-Specific Agreement (\\"CSA\\") will be a valid and binding agreement for all purposes relating to this InnoCentive Challenge and in addition to your agreement to abide by the Terms of Use when you registered as a Solver.   [更多]

求他克莫司片缓释胶囊大生产工艺及相关研究   [更多]

需要完整的甲苯磺酸妥舒沙星中试（公斤级）工艺；完整工艺杂质研究、初步的质控标准。   [更多]

在合理合法的范围内   [更多]

成本，生产周期，产品质量，工艺规模请列出。   [更多]

合理的大生产工艺即可或中试工艺   [更多]

基因治疗的概念出现在几十年前,当研究人员推测,人类疾病可以通过精确使用一种技术引入外来DNA来解决遗传缺陷和疾病症状。近年来，基因治疗的进步已经涉足治疗遗传疾病，癌症，神经退行性疾病等各领域。遗传性疾病如色素性视网膜炎等少数眼部疾病的基因也可以如此治疗。公司征集一种在人类眼部组织定性和定量(半)测量体内基因表达的方法。 具体如下https://www.innocentive.com/ar/challenge/9933643 The concept of gene therapy arose decades ago, when researchers postulated that human diseases could be treated by using a technique to introduce foreign DNA to correct genetic defects and disease phenotypes. In recent years, advances in gene therapy have been documented in the treatment of genetic disorders, cancer, and neurodegenerative diseases. Inherited diseases such as retinitis pigmentosa are among a handful of ocular diseases that are amenable to gene therapy. The Seeker desires solutions that will both qualitatively and (semi-) quantitatively measure in vivo gene expression in human ocular tissues. This Challenge requires only a written proposal. Source: InnoCentive Challenge ID: 9933643 Challenge Overview The number of clinical trials for gene therapy to treat ocular disorders is on the rise. Inherited diseases such as retinitis pigmentosa among others are thought to be good candidates for targeted treatment. Currently, there is no method in humans to determine the level or geographic location of transgene expression following administration of gene therapy for diseases of the eye, specifically the retina. The Seeker desires solutions that will both qualitatively and (semi-) quantitatively measure in vivo gene expression in human ocular tissues. Submissions to this Challenge must be received by 11:59 PM (US Eastern Time) on June 20, 2015. Late submissions will not be considered. This is a Theoretical Challenge that requires only a written proposal to be submitted. The Challenge award will be contingent upon theoretical evaluation of the proposal by the Seeker. To receive an award, Solvers will not be required to transfer their exclusive IP rights to the Seeker. Instead, Solvers will grant to the Seeker a   [更多]

具体要求：　要求工艺成熟,具有成本优势.   [更多]