72 累计需求单数
¥3,113,910.0 累计需求金额
0 违规次数

总金额为15000美金,寻找调动,刺激和分化内源性干细胞的方法。

悬赏
未托管赏金
¥0.00
  1. 发布需求
  2. 药智客交稿
  3. 任务主选稿中
  4. 选满结束
  1. 任务结束
任务结束
交易模式:
多人中标
赏金分配:
计件,每个¥0,已选0个,还需要10个
具体要求:
再生药的发展领域,主要集中在修复和取代受损细胞组织或病源组织。干细胞有自我修复功能。胚胎干细胞可以开发成身体内任何形式的细胞组织,成体干细胞的功能是维护或修复身体内部的细胞。Boiheringer Ingelheim的寻找目标是:调动,刺激,分化新的内源性干细胞分子结构的途径。


投标截止时期2016年6月24日,
投标网址:https://www.innocentive.com/ar/challenge/9933855 

原文
Mobilization, Stimulation, and Differentiation of Endogenous Stem Cells
 
TAGS: 
Chemistry, Royal Society of Chemistry, Life Sciences, Ideation
AWARD: $15,000 USD  |  DEADLINE: 6/24/16  |  ACTIVE SOLVERS: 51 |  POSTED: 4/25/16
1. The Challenge and qualification for the award
During early development, embryonic stem cells are undifferentiated cells that can be stimulated to proliferate and develop into all different cell types. In adults, these endogenous cells are found in tissues and they can divide either to replenish the stem cell population or differentiate into specialized cells of the tissue in which they reside. These adult stem cells function as an internal maintenance or repair system, so it would be beneficial to be able to direct and enhance this regenerative capacity. Therefore, Boehringer Ingelheim (the Seeker) desires the identification of new molecular mechanisms and pathways involved in mobilization, stimulation, and differentiation of endogenous stem cells. 
All submitted solutions will be considered for the award. There will be a guaranteed award for at least one submitted solution. The total payout will be $15,000, with the possibility to distribute it amongst one or more Solvers, with at least one award being no smaller than $5,000 and no award being smaller than $1,000. 
2. Additional application for Research Funding
In addition to consideration for the award for the submitted solutions, Solvers with appropriate qualifications and expertise having access to a suitable research laboratory and equipment can apply for research funding (“Research Funding”) to execute the research plan that is proposed in the solution. The selection of candidates for Research Funding will be conducted after completion of this Challenge and will require the submission of additional information. The decision to fund research will be at the discretion of the Seeker. 
This is an Ideation Challenge with a guaranteed award for at least one submitted solution.
Submissions to this Challenge including additional optional application for Research Funding must be received by 11:59 PM (US Eastern Time) on June 24, 2016. Late submissions will not be considered.
Source: InnoCentive      Challenge ID: 9933855
 
 
Sign Agreement For This Challenge
By electronically signing the agreement below, you are indicating your intention to view the details of this specific InnoCentive Challenge.
Viewing the Challenge Details does not obligate you to perform any work on this challenge. Print this Agreement for your records
InnoCentive Ideation Challenge-Specific Agreement
Please Read This Carefully!
You (hereinafter also the “Solver”) and InnoCentive, Inc (hereinafter “InnoCentive”) hereby agree on a Challenge-Specific Agreement for this particular InnoCentive Ideation Challenge only. The Seeker for this InnoCentive Challenge has required that you accept these special terms, so please take the time to understand them.
Please note that terms not expressly defined herein shall have the same meaning as defined in the Solver Terms of Use or as provided in any other document related to this specific InnoCentive Challenge.
If you click \\"I agree\\" and proceed to the Project Room for this InnoCentive Challenge, this Challenge-Specific Agreement (\\"CSA\\") will be a valid and binding agreement for all purposes relating to this InnoCentive Challenge (including your potential application for Research Funding) and will be applicable in addition to your agreement to abide by the Solver Terms of Usewhen you registered as a Solver. Please print and keep a copy of this CSA.
No provisions of any other agreement regarding other InnoCentive Challenges you may have agreed to earlier will apply to this specific InnoCentive Challenge.
1.	Proposed Solutions. As a Solver you may submit to InnoCentive your idea (your \\"Proposed Solution\\") to the InnoCentive Ideation Challenge to which this CSA relates (\\"InnoCentive Challenge®\\"). InnoCentive will make reasonable efforts to transmit Proposed Solutions to Seekers; however, nothing herein shall be construed as requiring InnoCentive to transmit every Proposed Solution on an InnoCentive Challenge to a Seeker. In addition, by submitting your Proposed Solution you thereby agree to provide reasonable assistance and additional information concerning your Proposed Solution to InnoCentive or the Seeker, if requested.
 
2.	Application for Research Funding. As a Solver you may, in addition to the provision of the Proposed Solution, apply for Seeker’s Research Funding as outlined in the InnoCentive Challenge Statement. The application for such additional option is only open to you if you (i) provide an additional research plan together with the Proposed Solution, (ii) are appropriately qualified and experienced to execute such research plan, (iii) have access to a suitable research laboratory and equipment, and (iv) are willing to enter into a research collaboration with the Seeker. The statement “I would like to be considered for research funding. I am affiliated with a research institution and have access to a suitable research laboratory and equipment.” must be expressly included in the application for Research Funding. By applying for Research Funding you agree that you receive Seeker contact information for the subsequent negotiation of a research collaboration should your application for Research Funding be selected by the Seeker. By contacting the Seeker you agree to provide contact and other personal information to the Seeker. Awarding a solution is independent from and does not automatically lead to a selection for Research Funding.
 
3.	Acceptance of Proposed Solution. InnoCentive will notify you within a commercially reasonable period of time after the end of the time period set forth in the InnoCentive Challenge Statement whether your Proposed Solution has been selected by Seeker for an Award. The Seeker will judge all Proposed Solutions against the guidelines set out in the InnoCentive Challenge Statement and determine, in its sole discretion, which Proposed Solution best addresses the InnoCentive Challenge Statement guidelines. The Seeker has absolute and sole discretion to determine whether to accept your Proposed Solution, or any Proposed Solution, and whether to make an Award, or multiple Awards. Solver acknowledges and agrees that InnoCentive is not responsible for and has no liability for selection of a winning solver.  Solver further agrees to hold InnoCentive legally harmless in regard to selection of a winning solver. Solver agrees to hold InnoCentive legally harmless for any advice it may provide as to the quality or suitability of submitted solutions and agrees to waive any claim against InnoCentive for Solver\'s failure to win an award. The meeting of the InnoCentive Challenge Statement guidelines does not automatically mean that the Proposed Solution will be eligible for an Award. Proposed Solutions must NOT contain or include ideas, concepts, solutions or technology in respect of which a third party owns or controls the intellectual property. Proposed Solutions and descriptions thereof may not include trademarks or trade names of corporations or entities without the permission of their owners.
 
4.	By entering, you represent and warrant that:
•	your entire Proposed Solution is an original work by you and you have not included third-party content (such as writing, text, graphics, artwork, logos, photographs, dialogue from plays, likeness of any third party, musical recordings, clips of videos, television programs or motion pictures) in or in connection with your Proposed Solution, unless (a) otherwise requested by the Seeker and/or disclosed by you in your Proposed Solution, and (b) you have either obtained the rights to use such third-party content or the content of the Proposed Solution is considered in the public domain without any limitations on use;
•	no person or entity other than you has any right, title or interest in any part of your Proposed Solution;
•	unless otherwise disclosed in the Proposed Solution, the use thereof by Seeker, or the exercise by Seeker of any of the rights granted by you under this Agreement, does not and will not infringe or violate any rights of any third party or entity, including, without limitation patent, copyright, trademark, trade secret, defamation, privacy, publicity, false light, misappropriation, intentional or negligent infliction of emotional distress, confidentiality, or any contractual or other rights;
•	you have all the rights, licenses, permissions and consents necessary to submit the Proposed Solution and to grant all of the rights that you have granted to Seeker hereunder, including the right for Seeker to use and develop derivative works of and from the Proposed Solution;
•	all persons who were engaged by you to work on the Proposed Solution or who appear in the Proposed Solution in any manner have:
a.	given you their express written consent to submit the Proposed Solution for unlimited, royalty-free use, exhibition and other exploitation in any manner and in any and all media, whether now existing or hereafter discovered, throughout the world, in perpetuity;
b.	provided written permission to include their name, image or pictures in or with your Proposed Solution (or if a minor who is not your child, you must have the permission of their parent or legal guardian) and you may be asked by Seeker to provide permission in writing;
c.	no claims for payment of any kind, including, without limitation, for royalties or residuals, has no approval or consultation rights or any rights of participation arising out of any use, exhibition or other exploitation of the Proposed Solution; and
d.	not been and are not currently under any union or guild agreement that results in any ongoing obligations resulting from the use, exhibition or other exploitation of the Proposed Solution; and
•	you understand, recognize and accept that Seeker has access to, may create or has created materials and ideas which may be similar or identical to the Proposed Solution in concept, theme, idea, format or other respects. You acknowledge and agree that Seeker shall have the right to use such same or similar materials, and that you will not be entitled to any compensation arising from Seeker\'s use of such materials. In the event that your entry is identical or similar to the Proposed Solution of another Solver, Seeker reserves the right, at the sole discretion of the Seeker, to either score one Proposed Solution higher than the other subject to the InnoCentive Challenge Statement guidelines or to randomly choose a Proposed Solution from all of those submitted which respond to the InnoCentive Challenge Statement guidelines.
Please also be aware that your Proposed Solution may not be acknowledged and will not be received or held \\"in confidence\\" and your Proposed Solution does not create a confidential relationship or obligation of secrecy between you and any of the entities involved in this Challenge.
5.	License to use. By entering Solver agrees that all tangible or digital copies of the submitted Proposed Solutions become Seeker\'s property and will not be returned. Each Solver agrees to grant to seeker, by submitting the Proposed Solution, to the fullest extent permissible by applicable law a non-exclusive, royalty free, worldwide, irrevocable, perpetual, assignable and sub-licensable license to the intellectual property rights in the idea or concept demonstrated by the Proposed Solution, in particular for the purpose of research, development, manufacturing and/or commercial use. This license includes the right to use, make, have made, market, copy, lease, sell distribute, and create derivate works of the Proposed Solution and the intellectual property rights in the idea or concept demonstrated by the Proposed Solution. Such right further contains the right to modify and adapt the Proposed Solution and to use the modified solution in the above extent. In addition, Seeker and its licensees, successors and assignees have the right to use any and all Proposed Solutions, and the names, likenesses, voices and images of all persons appearing in the Proposed Solution, for future advertising, promotion and publicity in any manner and in any medium now known or hereafter devised throughout the world in perpetuity.
 
6.	Ownership of intellectual property rights. For the avoidance of doubt, all intellectual property rights, if any, in the idea or concept demonstrated by the Proposed Solution to this challenge will remain with the solver.
 
7.	Payments. If a Seeker Accepts your Proposed Solution, the payment amount (called an \\"Award\\") specified in the InnoCentive Challenge posted on the Service by a Seeker (or, in the case of partial payments of Awards, a \\"Revised Award Amount\\", if applicable) shall be paid to you by InnoCentive within thirty (30) days after occurrence of each of the following:  1) you are notified by lnnoCentive of your Proposed Solution’s acceptance, and 2) the completion of certain verification procedures by InnoCentive, and review and acceptance of such results by Seeker, and 3) InnoCentive’s receipt of Award payment from the Seeker. Payment of any Award is conditioned upon your cooperation with InnoCentive\'s verification procedures. The Award will be paid to you locally, in U.S. Dollars, or if required by your local law, in your local currency equivalent based on the foreign exchange rate in effect on the date of the disbursement by InnoCentive. InnoCentive is not responsible for payment of any Award, or any part of any Award, to any party other than to the Solver through whom the Proposed Solution was submitted to the Service. You understand that the Award represents a complete payment, net of any local taxes that InnoCentive may be required to withhold, for any Accepted Proposed Solution and that you are not entitled to any other compensation of any kind. If local law does not require withholding of taxes, all taxes on Awards shall be your sole responsibility.
 
8.	GENERAL CONDITIONS, Personal Data. InnoCentive and/or Seeker has the right to verify each Solver\'s eligibility and compliance with this CSA, and to terminate any Solver’s registration or participation in a Challenge on the basis of its investigation. 
Participation is conditioned on providing the data required on the online registration form. Personal data will be processed in accordance with InnoCentive\'s Privacy Policy which can be located athttp://www.innocentive.com/privacy.php. Solvers should direct any request to access, update, or correct information to InnoCentive. Neither InnoCentive nor Seeker is responsible for human error, theft, destruction, or damage to Proposed Solutions, or other factors beyond its reasonable control. InnoCentive is solely responsible for the utilization of its platform by Solvers and Seekers; the Seeker in no event intends to commission any processing of personal data to InnoCentive while using the InnoCentive platform.
Solvers should not register with multiple e-mail and/or street addresses. In the event of a dispute as to any Proposed Solution, the authorized account holder of the email address used to enter will be deemed to be the person who submitted the Proposed Solution. The authorized \\"account holder\\" is the natural person assigned an email address by an Internet access provider, online service provider or other organization responsible for assigning email addresses for the domain associated with the submitted address.
9.	Representations and Warranties. You represent and warrant that:
•	All information provided by you regarding yourself and, if applicable, your business (\\"Solver Information\\") is true, accurate, current, and complete information and you will maintain and update the Solver Information to keep it true, accurate, current and complete.
•	If you are an individual representing a business or other entity, you are authorized to enter into this CSA on behalf of that business or entity.
•	Unless otherwise disclosed in the Proposed Solution, you are the owner of the Proposed Solution and the Proposed Solution does not infringe or violate any patent, copyright, trade secret, trademark or other third-party intellectual property right.
•	You have the right to grant the license in the Proposed Solution as required by Section 2 of this CSA.
•	In the event any of above obligation has been infringed by Solver, Solver shall indemnify and hold harmless the seeker from all damages, liabilities, and/or penalties claimed by third parties due to the infringement of their intellectual property right.
10.	Third Party Beneficiary. You and InnoCentive acknowledge and agree that the Seeker shall be a third-party beneficiary of this CSA, and shall have the right to assert and enforce the provisions of this CSA directly on its own behalf.
 
11.	Conflict. In the case of any conflict between the terms of this CSA and the Solver Terms of Use, this CSA controls.

				
2016-05-16 17:23
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